By S. Nassir Ghaemi
There is a professor of psychiatry available in the market who does a greater activity than Nassir Ghaemi in transmitting his knowledge on to you - yet in two decades i haven't chanced on one. i've got learn the authors study papers for years. As an editor, I grew to become acquainted with his publication "The techniques of Psychiatry" as I thought of the philosophical features of the sphere. His writing is usually transparent and his considering regularly brilliant.
In this short quantity on records and epidemiology his historic and unique observations and outlines of modern options is definitely worth the cost of buy on my own. a great instance is his bankruptcy on meta-analysis. He reminds the reader why this statistical technique used to be invented within the first position and is going directly to speak about major barriers, major historic evaluations, and the place the strategy might actually help. His evaluations are good idea in and out a couple of short pages he touches on matters that appear to be infrequently mentioned within the literature. this is often a huge bankruptcy for a doctor to learn in the course of a time whilst progressively more meta-analyses are thought of the gospel and prove as entrance web page truths.
He additionally offers a "defense and feedback" of proof dependent drugs. He presents a philosophical context for the dialogue and reminds us of "the cult of the Swan-Ganz catheter". someone who used to be an intern or resident in in depth care settings within the Eighties and early Nineties can keep in mind the frequent use of this equipment regardless of the shortcoming of proof in randomized scientific trials (RCTs). It grew to become the normal of care regardless of the inability of facts. He will pay homage to Feinstein his unique observations that the proof for evidence-based medication is going past RCTs.
The last chapters are concise discussions of information and epidemiology yet they're whatever yet dry. An instance will be his dialogue of influence estimation and the quantity had to deal with or NNT strategy he describes the calculation and its merits. He is going directly to describe the which means of specific numbers and in addition why the context is necessary. He makes use of a well timed instance of the problem of antidepressants and whether they bring about suicidality.
This e-book succeeds as a quantity that could speedily carry the clinician and researcher in control on most present subject matters in facts and epidemiology in drugs. it's not a ebook that reports mathematical thought. It doesn't offer exhaustive calculations and examples. it's written for clinicians. it's a e-book which may supply a foundation for dialogue and seminars during this box for complex citizens utilizing a number of the author's references or fresh literature searches to examine particular recommendations. it will possibly even be constructed right into a even more entire textual content at the topic. Dr. Ghaemi brings a truly detailed standpoint to the subject material and he has produced a truly readable publication that I hugely recommend.
George Dawson, MD
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Additional resources for A Clinician’s Guide to Statistics and Epidemiology in Mental Health: Measuring Truth and Uncertainty
Eric Temple Bell (Salsburg, 2001; p. 234) The best way to reduce confounding bias in observational studies is stratification or regression. Stratification Stratification means that one sees how patients do with and without the potential confounder. With the example of a study of whether a toxin causes cancer, it is important to know how many smokers and non-smokers there are in the sample. If the toxin causes the same cancer rate in smokers as it does in non-smokers, then you can conclude that smoking does not explain the results.
The first RCT: the Kuala Lumpur insane asylum study A historical pause may be useful here. Ronald Fisher is usually credited with originating the concept of randomization. Fisher did so in the setting of agricultural studies in the 1920s: certain fields randomly received a certain kind of seed, others fields received other seeds. A. Bradford Hill is credited with adapting the concept to the first human randomized clinical trial (RCT), a study of streptomycin for pneumonia in 1948. Multiple RCTs in other conditions followed right away in the 1950s, the first in psychiatry involving lithium in 1952 and the antipsychotic chlorpromazine in 1954.
Multiple RCTs in other conditions followed right away in the 1950s, the first in psychiatry involving lithium in 1952 and the antipsychotic chlorpromazine in 1954. This is the standard history, and it is correct in the sense that Fisher and Hill were clearly the first to formally develop the concept Section 2: Bias of randomization and to recognize its conceptual importance for statistics and science. But there is a hidden history, one that is directly relevant to the mental health professions.
A Clinician’s Guide to Statistics and Epidemiology in Mental Health: Measuring Truth and Uncertainty by S. Nassir Ghaemi